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UCM53

Names

[ CAS No. ]:
1449468-52-3

[ Name ]:
UCM53

[Synonym ]:
3-[(3,4-Dihydroxybenzoyl)oxy]-1-naphthyl 3-chloro-4-hydroxybenzoate
Benzoic acid, 3-chloro-4-hydroxy-, 3-[(3,4-dihydroxybenzoyl)oxy]-1-naphthalenyl ester

Biological Activity

[Description]:

UCM53, a FtsZ inhibitor, is an antibacterial agent. UCM53 can inhibit the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis[1]

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Ruiz-Avila LB, et al. Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ. ACS Chem Biol. 2013 Sep 20;8(9):2072-83.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
744.4±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H15ClO7

[ Molecular Weight ]:
450.825

[ Flash Point ]:
404.0±32.9 °C

[ Exact Mass ]:
450.050629

[ LogP ]:
6.00

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.723


Related Compounds

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