NYC-488

Names

[ Name ]:
NYC-488

Biological Activity

[Description]:

Calpain Inhibitor-1 (compound 36) is a potent and selective cysteine protease calpain 1 (Cal1) inhibitor (IC50=100 nM; Ki=2.89 μM)[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome

Research Areas >> Neurological Disease

[References]

[1]. Schiefer IT, Tapadar S, Litosh V, et al. Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. J Med Chem. 2013;56(15):6054-6068.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₇FN₆O₅S

[ Molecular Weight ]:
460.44

Related Compounds

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