PDE5-IN-6c

Names

[ Name ]:
PDE5-IN-6c

Biological Activity

[Description]:

A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1; displays >500-fold selectivity over PDE6; exhibits good efficacy in mouse model of Alzheimer's disease.

[References]

References 1. Fiorito J, et al. J Med Chem. 2017 Nov 9;60(21):8858-8875. View Related Products by Target Phosphodiesterase (PDE)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₁ClN₄O₂

[ Molecular Weight ]:
420.897

Related Compounds

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