PDE5-IN-5

Names

[ CAS No. ]:
2414921-33-6

[ Name ]:
PDE5-IN-5

Biological Activity

[Description]:

PDE5-IN-5 (Compound 11) is a potent, selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 2.0 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

[Target]

PDE5:2.0 nM (IC50)


[References]

[1]. ElHady AK, et al. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103742.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H20BrN3O4

[ Molecular Weight ]:
482.33

Related Compounds