GAT228

Names

[ Name ]:
GAT228

[Synonym ]:
1H-Indole, 3-[(1R)-2-nitro-1-phenylethyl]-2-phenyl-
3-[(1R)-2-Nitro-1-phenylethyl]-2-phenyl-1H-indole
R-(+)-3-(2-Nitro-1-phenylethyl)-2-phenyl-1H-indole
GAT228

Biological Activity

[Description]:

GAT228, the enantiomer of GAT211, is an allosteric cannabinoid receptor 1 (CB1) ligand[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor

[In Vivo]

GAT228 reduces pain scores in response to capsaicin stimulation[1].

[References]

[1]. Dinesh Thapa, et al. Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation. Molecules. 2020 Jan 20;25(2):417.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
585.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₂H₁₈N₂O₂

[ Molecular Weight ]:
342.391

[ Flash Point ]:
308.1±30.1 °C

[ Exact Mass ]:
342.136841

[ LogP ]:
6.23

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.668

Related Compounds

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