Cemdisiran

Names

[ Name ]:
Cemdisiran

Biological Activity

[Description]:

Cemdisiran is an N-acetylgalactosamine (GalNAc) conjugated siRNA for the treatment of complement-mediated diseases by suppressing liver production of complement 5 (C5) protein.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Immunology/Inflammation >> Complement System

[References]

[1]. Badri P, Jiang X, Borodovsky A, et al. Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal Nocturnal Hemoglobinuria. Clin Pharmacokinet. 2021;60(3):365-378.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₈H₁₄₀N₁₁O₃₄P

[ Molecular Weight ]:
1806.97

Related Compounds

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