<Suppliers Price>

JTV-519 hemifumarate

Names

[ CAS No. ]:
1435938-25-2

[ Name ]:
JTV-519 hemifumarate

Biological Activity

[Description]:

JTV-519 hemifumarate (K201 hemifumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1].

[References]

[1]. Darcy YL, et al. K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle. Mol Pharmacol. 2016 Aug;90(2):106-15.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H32N2O2S.1/2C4H4O4

[ Molecular Weight ]:
482.64

Related Compounds