Nicardipine D3 hydrochloride

Names

[ CAS No. ]:
1432061-50-1

[ Name ]:
Nicardipine D3 hydrochloride

[Synonym ]:
2-{Benzyl[(2H3)methyl]amino}ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1)
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-[methyl-d3(phenylmethyl)amino]ethyl ester, hydrochloride (1:1)

Biological Activity

[Description]:

Nicardipine D3 hydrochloride (YC-93 D3) is the deuterium labeled Nicardipine hydrochloride. Nicardipine hydrochloride is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Neurological Disease

[References]

[1]. Charnet P, et al. Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers. Fundam Clin Pharmacol. 1987;1(6):413-31.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₇D₃ClN₃O₆

[ Molecular Weight ]:
519.004

[ Exact Mass ]:
518.201172

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.