(R)-Irsenontrine

Names

[ Name ]:
(R)-Irsenontrine

Biological Activity

[Description]:

(R)-Irsenontrine ((R)-E2027), the R-enantiomer of Irsenontrine (HY-132821), is a potent phosphodiesterase 9 (PDE9) inhibitor with an IC50 value of 0.041 μM. (R)-Irsenontrine can be used for the research of neurological diseases[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

Research Areas >> Neurological Disease

[Target]

PDE9:0.041 μM (IC50)

[References]

[1]. Yoshihiko N, et, al. Pyrazoloquinoline derivative. WO2013051639A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₂N₄O₃

[ Molecular Weight ]:
390.44

Related Compounds

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