Retro-2 cycl

Names

[ Name ]:
Retro-2 cycl

[Synonym ]:
rn-1-001

Biological Activity

[Description]:

Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC50s of 54 μM and 160 μM, respectively[1]. Antiviral agent[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Carney DW, et al. Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem. 2014 Sep 1;22(17):4836-47.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₆N₂OS

[ Molecular Weight ]:
320.41

[ Exact Mass ]:
320.09800

[ PSA ]:
60.58000

[ LogP ]:
5.03060

[ Storage condition ]:
2-8℃

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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