Macrocarpal E

Names

[ Name ]:
Macrocarpal E

[Synonym ]:
2,4,6-Trihydroxy-5-{1-[6-(2-hydroxy-2-propanyl)-4,8a-dimethyl-1,2,3,4,6,7,8,8a-octahydro-1-naphthalenyl]-3-methylbutyl}isophthalaldehyde
2,4,6-trihydroxy-5-(1-(8-(1-hydroxy-isopropyl)-1,5-dimethylbicyclo(4.4.0)dec-6-en-2-yl)-3-methylbutyl)benzene-1,3-dicarbaldehyde
Macrocarpal E
2,4,6-trihydroxy-5-{1-[8-(1-hydroxy-isopropyl)-1,5-dimethylbicyclo[4.4.0]dec-6-en-2-yl]-3-methylbutyl}benzene-1,3-dicarbaldehyde
1,3-Benzenedicarboxaldehyde, 2,4,6-trihydroxy-5-[(1R)-3-methyl-1-[(1S,4S,6R,8aS)-1,2,3,4,6,7,8,8a-octahydro-6-(1-hydroxy-1-methylethyl)-4,8a-dimethyl-1-naphthalenyl]butyl]-
2,4,6-Trihydroxy-5-{(1R)-1-[(1S,4S,6R,8aS)-6-(2-hydroxy-2-propanyl)-4,8a-dimethyl-1,2,3,4,6,7,8,8a-octahydro-1-naphthalenyl]-3-methylbutyl}isophthalaldehyde
1,3-Benzenedicarboxaldehyde, 2,4,6-trihydroxy-5-[3-methyl-1-[1,2,3,4,6,7,8,8a-octahydro-6-(1-hydroxy-1-methylethyl)-4,8a-dimethyl-1-naphthalenyl]butyl]-

Biological Activity

[Description]:

Macrocarpal E is a potent antibacterial agent. Macrocarpal E is a phloroglucinol dialdehyde diterpene derivatives that can be found in the leaves of Eucalyptus macrocarpa[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Macrocarpal E 显示抗菌活性，对 Staphylococcus aureus FAD209P, Micrococcus luteus ATCC9341, Bacillus subtiUs PCI2l9, Mycobacterium smegmatis ATCC607 的 MIC 值分别为 0.78、3.13、0.39、0.78 µg/mL[1]。

[References]

[1]. Yamakoshi Y, et al. Isolation and characterization of macrocarpals B--G antibacterial compounds from Eucalyptus macrocarpa. Biosci Biotechnol Biochem. 1992 Oct;56(10):1570-6.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
552.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₄₀O₆

[ Molecular Weight ]:
472.614

[ Flash Point ]:
301.7±26.6 °C

[ Exact Mass ]:
472.282501

[ PSA ]:
115.06000

[ LogP ]:
9.11

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.588

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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