UNC 2327

Names

[ Name ]:
UNC 2327

[Synonym ]:
UNC2327
Urea, N-1,2,3-benzothiadiazol-6-yl-N'-[2-oxo-2-(1-piperidinyl)ethyl]-
1-(1,2,3-Benzothiadiazol-6-yl)-3-[2-oxo-2-(1-piperidinyl)ethyl]urea

Biological Activity

[Description]:

UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[Target]

PRMT3

[References]

[1]. Liu F, et al. Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J Med Chem. 2013 Mar 14;56(5):2110-24.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₁₄H₁₇N₅O₂S

[ Molecular Weight ]:
319.382

[ Exact Mass ]:
319.110291

[ LogP ]:
1.71

[ Index of Refraction ]:
1.686

Related Compounds

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