Deacetylasperulosidic acid

Names

[ Name ]:
Deacetylasperulosidic acid

[Synonym ]:
10-Deacetylasperulosidic acid
desacetyl asperulosidic acid
deacethyl asperulosidic acid
(1S,4aS,5S,7aS)-1-(β-D-Glucopyranosyloxy)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid
10-Desacetylasperulosidic acid
Deacetylasperulosidic acid
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)-, (1S,4aS,5S,7aS)-

Biological Activity

[Description]:

Deacetylasperulosidic acid (DAA) is a major phytochemical constituent of Morinda citrifolia fruit. Deacetylasperulosidic acidhas antioxidant activity by increasing superoxide dismutase activity. Deacetylasperulosidic acid has anticlastogenic activity, suppressing the induction of chromosome aberrations in hamster ovary cells and mice[1]. Deacetylasperulosidic acid prevents 4-nitroquinoline 1-oxide (4NQO) induced DNA damage in vitro, suppresses IL-2 production along with the activation of natural killer cells[2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related

Research Areas >> Inflammation/Immunology

[References]

[1]. Ma DL, et al. In vivo antioxidant activity of deacetylasperulosidic Acid in noni. J Anal Methods Chem. 2013;2013:804504.

[2]. Murata K, et al. Activation of cell-mediated immunity by Morinda citrifolia fruit extract and its constituents. Nat Prod Commun. 2014 Apr;9(4):445-50.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
744.1±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₂₂O₁₁

[ Molecular Weight ]:
390.339

[ Flash Point ]:
271.7±26.4 °C

[ Exact Mass ]:
390.116211

[ PSA ]:
186.37000

[ LogP ]:
-2.48

[ Vapour Pressure ]:
0.0±5.6 mmHg at 25°C

[ Index of Refraction ]:
1.683

Related Compounds

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