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Glyasperin C

Names

[ CAS No. ]:
142474-53-1

[ Name ]:
Glyasperin C

[Synonym ]:
4-[(3R)-7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]benzene-1,3-diol
Glyasperin C

Biological Activity

[Description]:

Glyasperin C is a potent and reversible noncompetitive inhibitor of neuraminidase with an IC50 of 20% at 200 μM. Glyasperin C is a polyphenol isolated from the roots of Glycyrrhiza uralensis[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[Target]

neuraminidase[1]


[References]

[1]. Ryu YB, et al. Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis. Bioorg Med Chem Lett. 2010;20(3):971-974.

Chemical & Physical Properties

[ Density]:
1.243g/cm3

[ Boiling Point ]:
559.3ºC at 760mmHg

[ Molecular Formula ]:
C21H24O5

[ Molecular Weight ]:
356.41200

[ Flash Point ]:
292ºC

[ Exact Mass ]:
356.16200

[ PSA ]:
79.15000

[ LogP ]:
4.03940

[ Vapour Pressure ]:
4.09E-13mmHg at 25°C

[ Index of Refraction ]:
1.616


Related Compounds

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