DL-Valine-d1

Names

[ CAS No. ]:
14246-21-0

[ Name ]:
DL-Valine-d1

[Synonym ]:
Glucosamineoximehydrochlorid
D-Glucosamine-oximeHCI
D-Glucosamine-oxime hydrochlorid
D-Glucosamine-oximeHCl
2-amino-2-deoxy-d-glucose oxime,hydrochloride
2-Amino-2-desoxy-d-glucose-oxim,Hydrochlorid
2-amino-2-deuterio-3-methyl-butyric acid

Biological Activity

[Description]:

DL-Valine-d1 is the deuterium labeled DL-Valine[1].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.073 g/cm3

[ Boiling Point ]:
213.642ºC at 760 mmHg

[ Melting Point ]:
295ºC (subl.)(lit.)

[ Molecular Formula ]:
C5H10DNO2

[ Molecular Weight ]:
118.15

[ Flash Point ]:
83.008ºC

[ Exact Mass ]:
118.08500

[ PSA ]:
63.32000

[ LogP ]:
0.75460

Synthetic Route

Precursor & DownStream


Related Compounds