DL-Valine-d8

Names

[ CAS No. ]:
203784-63-8

[ Name ]:
DL-Valine-d8

[Synonym ]:
DL-Valine-2,3,4,4,4,5,5,5-d8
MFCD00144194
DL-Valine-d8

Biological Activity

[Description]:

DL-Valine-d8 is the deuterium labeled DL-Valine[1].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.136g/cm3

[ Boiling Point ]:
213.6ºC at 760 mmHg

[ Melting Point ]:
295ºC (subl.)(lit.)

[ Molecular Formula ]:
C₅H₃D₈NO₂

[ Molecular Weight ]:
125.20

[ Flash Point ]:
83ºC

[ Exact Mass ]:
125.12900

[ PSA ]:
63.32000

[ LogP ]:
0.75460

[ Vapour Pressure ]:
0.0633mmHg at 25°C

[ Index of Refraction ]:
1.461

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport