EMICORON

Names

[ Name ]:
EMICORON

[Synonym ]:
Dibenzo[10,11:4,5]chryseno[2,1,12-def]isoquinoline-1,3,8,10(2H,9H)-tetrone, 13-(1-piperidinyl)-2,5,9-tris[2-(1-piperidinyl)ethyl]-
13-(1-Piperidinyl)-2,5,9-tris[2-(1-piperidinyl)ethyl]naphtho[3',2',1',8',7':1,12,11]tetrapheno[9,8,7-def]isoquinoline-1,3,8,10(2H,9H)-tetrone
MFCD31563581

Biological Activity

[Description]:

Emicoron is a new promising G4 ligand and bind G-rich oncogene promoters. Emicoron possesses a marked antitumoral activity? alone or in combination with chemotherapeutics in vivo. Emicoron can be used for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> G-quadruplex

[References]

[1]. Manuela Porru, et al. EMICORON: A multi-targeting G4 ligand with a promising preclinical profile. Biochim Biophys Acta Gen Subj. 2017 May; 1861(5 Pt B):1362-1370.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C₅₃H₅₉N₅O₄

[ Molecular Weight ]:
830.067

[ Exact Mass ]:
829.456726

[ LogP ]:
8.39

[ Index of Refraction ]:
1.721

Related Compounds

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