Phoenixin-20

Names

[ CAS No. ]:
1415039-77-8

[ Name ]:
Phoenixin-20

Biological Activity

[Description]:

Phoenixin-20 (PNX-20) is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect[1][2][3].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[References]

[1]. Yang Y, et al. Phoenixin 20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. J Mol Histol. 2020;51(2):173-181.  

[2]. Rajeswari JJ, et al. Phoenixin-20 Stimulates mRNAs Encoding Hypothalamo-Pituitary-Gonadal Hormones, is Pro-Vitellogenic, and Promotes Oocyte Maturation in Zebrafish. Sci Rep. 2020;10(1):6264.  

[3]. Jiang JH, et al. Effects of Phoenixin-14 on anxiolytic-like behavior in mice. Behav Brain Res. 2015;286:39-48.  

Chemical & Physical Properties

[ Molecular Formula ]:
C101H153N25O29

[ Molecular Weight ]:
2181.45

Related Compounds

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