Tr-PEG5-OH

Names

[ Name ]:
Tr-PEG5-OH

[Synonym ]:
2,5,8,11,14-Pentaoxahexadecan-16-ol,1,1,1-triphenyl
2-(2-{2-[2-(trityloxyethoxy)ethoxy]ethoxy}ethoxy)ethanol
TrO-PEG5-OH
2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethanol
16,16,16-triphenyl-3,6,9,12,15-pentaoxahexadecanol

Biological Activity

[Description]:

Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

Research Areas >> Inflammation/Immunology

[Target]

Non-cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Branderhorst HM, et al. Strong inhibition of cholera toxin binding by galactose dendrimers. Chem Commun (Camb). 2007 Dec 21;(47):5043-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₆O₆

[ Molecular Weight ]:
480.59300

[ Exact Mass ]:
480.25100

[ PSA ]:
66.38000

[ LogP ]:
4.05380

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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