Gamma-Tocotrienol

Names

[ Name ]:
Gamma-Tocotrienol

[Synonym ]:
(2R)-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol
(2R)-2,7,8-Trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]chroman-6-ol
(2R)-2,7,8-Trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-6-chromanol
gamma-tocotrienol
γ-Tocotrienol
2H-1-benzopyran-6-ol, 3,4-dihydro-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-, (2R)-
BOC-N-methyl-2-napthylalanine
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-, (2R)-
D-γ-Tocotrienol

Biological Activity

[Description]:

γ-Tocotrienol is an active form of vitamin E[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

[References]

[1]. M A Newaz, et al. Nitric Oxide Synthase Activity in Blood Vessels of Spontaneously Hypertensive Rats: Antioxidant Protection by Gamma-Tocotrienol. J Physiol Pharmacol. 2003 Sep;54(3):319-27.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
530.8±49.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₄₂O₂

[ Molecular Weight ]:
410.632

[ Flash Point ]:
218.4±24.1 °C

[ Exact Mass ]:
410.318481

[ PSA ]:
29.46000

[ LogP ]:
10.30

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.523

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

Plastochromanol-8: fifty years of research.

Phytochemistry 108 , 9-16, (2014)

Plastochromanol-8 (PC-8) is an antioxidant that, together with tocopherols and tocotrienols, belongs to the group of tocochromanols. Plastochromanol-8 has been found to occur in several plant species,...

Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity.

Cell Prolif. 46(2) , 203-13, (2013)

Tocotrienols and tocopherols are members of the vitamin E family, with similar structures; however, only tocotrienols have been reported to achieve potent anti-cancer effects. The study described here...

Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol.

J. Nutr. Sci. Vitaminol. 57(5) , 326-32, (2011)

We previously found that 2,7,8-trimethyl-2(2'-carboxyethyl)-6-hydroxychroman (_CEHC), a metabolite of the vitamin E isoforms _-tocopherol or _-tocotrienol, accumulated in the rat small intestine. The ...