2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite

Names

[ Name ]:
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite

Biological Activity

[Description]:

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₆H₅₁FN₅O₈P

[ Molecular Weight ]:
851.9

[ Storage condition ]:
2-8℃

Related Compounds

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