DNMT3A-IN-1

Names

[ CAS No. ]:
1403598-56-0

[ Name ]:
DNMT3A-IN-1

Biological Activity

[Description]:

DNMT3A-IN-1 is a potent and selective DNMT3A inhibitor. DNMT3A-IN-1 shows inhibitor activities against DNMT3A with kI values range from 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC) [1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Epigenetics >> DNA Methyltransferase

[Target]

DNMT3A


[References]

[1]. Huang S, et al. A novel class of selective non-nucleoside inhibitors of human DNA methyltransferase 3A. Bioorg Med Chem Lett. 2021; 40:127908.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H38N6O4

[ Molecular Weight ]:
546.66

Related Compounds