Pterisolic acid B

Names

[ Name ]:
Pterisolic acid B

[Synonym ]:
(5β,6α,8α,10α,13α)-6-Hydroxy-15-oxokaura-9(11),16-dien-18-oic acid
Pterisolic acid B

Biological Activity

[Description]:

Pterisolic acid B (Compound 2) is an ent-Kaurane diterpenoid. Pterisolic acid B can be isolated from fern Pteris semipinnata (Pteridaceae)[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> Keap1-Nrf2

Research Areas >> Others

[References]

[1]. Ting Dong, et al. Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain. Sci Rep. 2016 Jan 13:6:19231.

[2]. Wang F, et al. Pterisolic acids A-F, new ent-kaurane diterpenoids from the fern Pteris semipinnata. Chem Pharm Bull (Tokyo). 2011;59(4):484-7.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
536.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₆O₄

[ Molecular Weight ]:
330.418

[ Flash Point ]:
292.4±26.6 °C

[ Exact Mass ]:
330.183105

[ PSA ]:
74.60000

[ LogP ]:
2.38

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.593

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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