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DS-3032b

Names

[ CAS No. ]:
1398568-47-2

[ Name ]:
DS-3032b

[Synonym ]:
R3I80TLN7S
DS-3032
milademetan

Biological Activity

[Description]:

Mliademetan is a specific MDM2 inhibitor, a pharmaceutical composition for use in treating acute myeloid leukemia (AML).

[Related Catalog]:

Signaling Pathways >> Apoptosis >> MDM-2/p53
Research Areas >> Cancer

[Target]

MDM2[1].


[References]

[1]. ARYL SULFONOHYDRAZIDES. WO 2017069289 A1.


[Related Small Molecules]

Pifithrin-α hydrobromide | RG7388 | Nutlin-3a | AMG232 | Pifithrin-β (hydrobromide) | Stylomycin aminonucleoside | RG7112 | APR-246 | NVP-HDM201 | SAR 405838 | RITA (NSC 652287) | NVP-CGM097 | Tenovin-1 | SJ 172550

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
840.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H34Cl2FN5O4

[ Molecular Weight ]:
618.526

[ Flash Point ]:
462.2±34.3 °C

[ Exact Mass ]:
617.197205

[ LogP ]:
3.54

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.646

[ Storage condition ]:
2-8℃


Related Compounds