Thiophanat-ethyl-d10

Names

[ CAS No. ]:
1398066-16-4

[ Name ]:
Thiophanat-ethyl-d10

[Synonym ]:
Carbamic acid, N,N'-[1,2-phenylenebis(iminocarbonothioyl)]bis-, diethyl-d5 ester
Topsin E-d10
Bis[(2H5)ethyl] (1,2-phenylenedicarbamothioyl)biscarbamate
Thiophanate-d10
Topsin-d10

Biological Activity

[Description]:

Thiophanat-ethyl-d10 is the deuterium labeled Thiophanat-ethyl[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C14H8D10N4O4S2

[ Molecular Weight ]:
380.51

[ Exact Mass ]:
380.139709

[ LogP ]:
2.22

[ Index of Refraction ]:
1.676

Related Compounds