Tenuifoliside B

Names

[ Name ]:
Tenuifoliside B

[Synonym ]:
3-O-[(2E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoyl]-β-D-fructofuranosyl 6-O-(4-hydroxybenzoyl)-α-D-glucopyranoside
Tenuifoliside B
α-D-Glucopyranoside, 3-O-[(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-β-D-fructofuranosyl, 6-(4-hydroxybenzoate)
F38VD25Q1W

Biological Activity

[Description]:

Tenuifoliside B, a component isolated from Polygalae Radix, inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. Tenuifoliside B shows potential cognitive improvement and cerebral protective effects. Tenuifoliside B has potential to become an anti-AD lead compound[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. YongjiangWu, et al. Studies on the total synthesis of tenuifoliside B. Tetrahedron. 2017 Jun.

[2]. Fumito KARAKIDA, et al. Cerebral Protective and Cognition-Improving Effects of Sinapic Acid in Rodents. Biol. Pharm. Bull. 30(3) 514-519 (2007).

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
926.1±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₃₆O₁₇

[ Molecular Weight ]:
668.597

[ Flash Point ]:
296.8±27.8 °C

[ Exact Mass ]:
668.195251

[ LogP ]:
3.19

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.670

[ Storage condition ]:
2-8℃

Related Compounds

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