Dunnial

Names

[ Name ]:
Dunnial

[Synonym ]:
5,5',5''-Triallyl-1,1':3',1''-terphenyl-2,2',2''-triol
[1,1':3',1''-Terphenyl]-2,2',2''-triol, 5,5',5''-tri-2-propen-1-yl-

Biological Activity

[Description]:

Dunnianol is a natural sesqui-neoligan with moderate antibacterial activity. Dunnianol inhibits Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA).

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Yong Guo, et al. Discovery, Synthesis, and Biological Evaluation of Dunnianol-Based Mannich Bases against Methicillin-Resistant Staphylococcus aureus (MRSA). ACS Infect Dis. 2020 Sep 11;6(9):2478-2489.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
525.4±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₂₆O₃

[ Molecular Weight ]:
398.493

[ Flash Point ]:
227.3±23.3 °C

[ Exact Mass ]:
398.188202

[ PSA ]:
60.69000

[ LogP ]:
5.66

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.622

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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