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Vps34-IN-1

Names

[ CAS No. ]:
1383716-33-3

[ Name ]:
Vps34-IN-1

[Synonym ]:
1-({2-[(2-Chloro-4-pyridinyl)amino]-4'-(cyclopropylmethyl)-4,5'-bipyrimidin-2'-yl}amino)-2-methyl-2-propanol
vps34-in1
2-Propanol, 1-[[2-[(2-chloro-4-pyridinyl)amino]-4'-(cyclopropylmethyl)[4,5'-bipyrimidin]-2'-yl]amino]-2-methyl-
Vps34-IN-1

Biological Activity

[Description]:

Vps34-IN-1 is an inhibitor of Vps34 extracted from patent WO2012085815A1, compound example 16a, with an IC50 of 4 nM.

[Related Catalog]:

Research Areas >> Cancer

[Target]

Vps34:4 nM (IC50)


[References]

[1]. WO/2012085815 A1


[Related Small Molecules]

3-Methyladenine | LY294002 | Wortmannin | Alpelisib (BYL719) | BKM120 | Eganelisib(IPI-549) | BAY 80-6946 (Copanlisib) | Idelalisib (CAL-101) | Dactolisib (BEZ235) | Quercetin | SAR-405 | GDC-0941 | 740 Y-P | LY3023414 | 1,3-Dicaffeoylquinic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
693.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H24ClN7O

[ Molecular Weight ]:
425.915

[ Flash Point ]:
373.4±34.3 °C

[ Exact Mass ]:
425.173096

[ LogP ]:
3.70

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.689

[ Storage condition ]:
-20℃

Related Compounds

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