Valsartan
Names
[ CAS No. ]:
137862-53-4
[ Name ]:
Valsartan
[Synonym ]:
Valsartan
(S)-N-(1-Carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]amine
N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}-L-valine
N-Pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine
N-Pentanoyl-N-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}valine
N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
(2S)-3-Methyl-2-(pentanoyl{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}amino)butanoic acid
N-[p-(o-1H-Tetrazol-5-ylphenyl)benzyl]-N-valeryl-L-valine
3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid
Nisis
N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valin
(2S)-3-Methyl-2-(pentanoyl{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}amino)butanoic acid
Valsratan
N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
Tareg
DIOVAN
L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
Valsartane
Valsartan API
(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid
L-Valsartan
MFCD00865840
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[In Vivo]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
684.9±65.0 °C at 760 mmHg
[ Melting Point ]:
116-117°C
[ Molecular Formula ]:
C24H29N5O3
[ Molecular Weight ]:
435.519
[ Flash Point ]:
368.0±34.3 °C
[ Exact Mass ]:
435.227051
[ PSA ]:
112.07000
[ LogP ]:
4.75
[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C
[ Index of Refraction ]:
1.587
[ Storage condition ]:
-20°C Freezer, Under inert atmosphere
[ Stability ]:
Hygroscopic
MSDS
Safety Information
[ Hazard Statements ]:
H413
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Luminescence 29(8) , 1148-53, (2014)
A highly sensitive, rapid and economical method for the determination of amlodipine (AM) in biological fluids was developed using a peroxyoxalate chemiluminescence (CL) system in a lab-on-a-chip devic...
Development and Validation of a LC-MS/MS Method for the Simultaneous Estimation of Amlodipine and Valsartan in Human Plasma: Application to a Bioequivalence Study.Sci. Pharm. 82(3) , 585-600, (2015)
A reliable, simple, and robust liquid chromatography-tandem mass spectro-metric (LC-MS/MS) method has been developed and validated that employs solid-phase extraction for the simultaneous estimation o...
Comparative study between derivative spectrophotometry and multivariate calibration as analytical tools applied for the simultaneous quantitation of Amlodipine, Valsartan and Hydrochlorothiazide.Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 113 , 215-23, (2013)
Four simple, accurate and specific methods were developed and validated for the simultaneous estimation of Amlodipine (AML), Valsartan (VAL) and Hydrochlorothiazide (HCT) in commercial tablets. The de...