Phosphate monobasic-d2 potassium

Names

[ Name ]:
Phosphate monobasic-d2 potassium

[Synonym ]:
Potassium dideuterophosphate
deuterated potassium dihydrogen phosphate
Potassium dideuterium phosphate
MFCD00074894
EINECS 237-357-9

Biological Activity

[Description]:

Phosphate monobasic-d2 (potassium) is the deuterium labeled Potassium phosphate monobasic[1]. Potassium phosphate monobasic (DiA) is a commonly used in biological assay buffers. Potassium phosphate monobasic is moderate to highly concentrated aqueous solutions of potassium phosphate monobasic for the production of phosphate buffers and other laboratory applications.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Boiling Point ]:
158ºC at 760 mmHg

[ Melting Point ]:
253ºC(lit.)

[ Molecular Formula ]:
D₂KO₄P

[ Molecular Weight ]:
138.09800

[ Exact Mass ]:
137.94500

[ PSA ]:
90.40000

[ Vapour Pressure ]:
1.41mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Controlling the taste receptor accessible structure of rebaudioside A via binding to bovine serum albumin.

Food Chem. 197 , 84-91, (2015)

We illustrate a method that uses bovine serum albumin (BSA) to control the receptor-accessible part of rebaudioside A (Reb A). The critical micelle concentration (CMC) of Reb A was found to be 4.5 mM ...