(S)-N-t-butyl decahydro-3-iso-quinolinecarboxamide
Names
[ CAS No. ]:
136465-81-1
[ Name ]:
(S)-N-t-butyl decahydro-3-iso-quinolinecarboxamide
[Synonym ]:
(S)-N-tert-Butyldecahydro-3-iso-quinolinecarboxamide
(S)-N-tert-Butyldecahydroisoquinoline-3-carboxaMide
N-tert-Butyldecahydroisoquinoline-3-carboxamide, (3S,4aS,8aS)
(S)-tert-Butyl decahydro-3-isoquinolinecarboxamide
[3S-(3a,4ab,8ab)]-N-(tert-Butyl)decahydro-3-isoquinolinecarboxamide
MFCD01313226
[3S-(3α,4aβ,8aβ)]-N-(tert-Butyl)decahydro-3-isoquinolinecarboxamide
3-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-, (3S,4aS,8aS)-
(3S,4aS,8aS)-N-tert-Butyldecahydroisoquinoline-3-carboxamide
T66 CMTJ DVMX1&1&1 &&(3S,4aS,8aS)- Form
(3S,4aS,8aS)-N-(2-Methyl-2-propanyl)decahydro-3-isoquinolinecarboxamide
EINECS 420-380-5
(3S,4aS,8aS)-N-(tert-Butyl)decahydroisoquinoline-3-carboxamide
(3S,4AS,8AS)-N-TERT-BUTYL DECAHYDRO ISOQUINOLINE-3-CARBOXAMIDE
(S)-N-t-butyl decahydro-3-iso-quinolinecarboxamide
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
401.5±24.0 °C at 760 mmHg
[ Melting Point ]:
112-115ºC
[ Molecular Formula ]:
C14H26N2O
[ Molecular Weight ]:
238.369
[ Flash Point ]:
146.7±23.0 °C
[ Exact Mass ]:
238.204514
[ PSA ]:
41.13000
[ LogP ]:
2.01
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.482
MSDS
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H318-H412
[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
22-41-52/53
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
J. Med. Chem. 35 , 2525, (1992)
A series of HIV-1 protease inhibitors containing a novel hydroxyethyl secondary amine transition state isostere has been synthesized. The compounds exhibit a strong preference for the (R) stereochemis...
Trova, M.P. et al.Bioorg. Med. Chem. Lett. 3 , 1595, (1993)