DBCO-Sulfo-Link-biotin

Names

[ CAS No. ]:
1363444-70-5

[ Name ]:
DBCO-Sulfo-Link-biotin

Biological Activity

[Description]:

DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Portnoff AD, et al. An antidote approach to reduce risk and broaden utility of antibody-based therapeutics. J Biol Chem. 2017 May 19;292(20):8498-8506.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₅N₅O₇S₂

[ Molecular Weight ]:
653.77

Related Compounds

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