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DBCO-Sulfo-NHS ester

Names

[ CAS No. ]:
1400191-52-7

[ Name ]:
DBCO-Sulfo-NHS ester

Biological Activity

[Description]:

DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Jung S, et al. Facile strategy for protein conjugation with chitosan-poly(ethylene glycol) hybrid microparticleplatforms via strain-promoted alkyne-azide cycloaddition (SPAAC) reaction. Biomacromolecules. 2013 Nov 11;14(11):3892-902.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H21N2NaO8S

[ Molecular Weight ]:
532.50

Related Compounds