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TAT 14TFA

Names

[ CAS No. ]:
1362661-34-4

[ Name ]:
TAT 14TFA

Biological Activity

[Description]:

TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> Keap1-Nrf2
Research Areas >> Others

[Target]

IC50: Nrf2[1]


[References]

[1]. Richard Steel, et al. Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction. ACS Med Chem Lett. 2012 May 10;3(5):407-410.

Chemical & Physical Properties

[ Molecular Formula ]:
C137H230N48O39

[ Molecular Weight ]:
3173.59

Related Compounds