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Wnt pathway activator 1

Names

[ CAS No. ]:
1360540-81-3

[ Name ]:
Wnt pathway activator 1

[Synonym ]:
1,4-Butanedione, 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-
1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-phenyl-1,4-butanedione

Biological Activity

[Description]:

Wnt pathway activator 1 is a potent Wnt activator extracted from patent WO2012024404A1, compound 1, has an IC50s of 28-29 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Stem Cell/Wnt >> Wnt

[Target]

IC50: 28-29 nM (Wnt)[1]


[References]

[1]. Charlene F. Barroga, et al. Diketones and hydroxyketones as catenin signaling pathway activators. WO2012024404A1.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
500.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H16O4

[ Molecular Weight ]:
296.317

[ Flash Point ]:
223.1±30.2 °C

[ Exact Mass ]:
296.104858

[ LogP ]:
3.36

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.586

[ Storage condition ]:
-20°C


Related Compounds

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