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Acremoxanthone C

Names

[ CAS No. ]:
1360445-63-1

[ Name ]:
Acremoxanthone C

Biological Activity

[Description]:

Acremoxanthone C is a potent calmodulin (CaM) inhibitor found in Purpureocillium lilacinum. Acremoxanthone C binds to the human calmodulin (hCaM) biosensor hCaM M124C-mBBr, with Kd of 18.25 nM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Neuronal Signaling >> CaMK

[Target]

Microbial Metabolite


[References]

[1]. Madariaga-Mazón A, et al. Absolute configuration of acremoxanthone C, a potent calmodulin inhibitor from Purpureocillium lilacinum. J Nat Prod. 2013;76(8):1454-1460.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H26O12

[ Molecular Weight ]:
614.55

Related Compounds