Kadsulactone acid

Names

[ Name ]:
Kadsulactone acid

[Synonym ]:
3-{6-Isopropenyl-3a,9a-dimethyl-1-[1-(5-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl]decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl}propanoic acid
1H-Cyclopenta[a]cyclopropa[e]naphthalene-6a(7H)-propanoic acid, 1-[(1S)-1-[(2R)-3,6-dihydro-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]decahydro-3a,9a-dimethyl-6-(1-methylethenyl)-, (1R,3aS,3bS,6S,6aR,7aS,9aR)-
3-[(1R,3aS,3bS,6S,6aR,7aS,9aR)-3a,9a-Dimethyl-1-{(1S)-1-[(2R)-5-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl}-6-(prop-1-en-2-yl)decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid
1H-Cyclopenta[a]cyclopropa[e]naphthalene-6a(7H)-propanoic acid, 1-[1-(3,6-dihydro-5-methyl-6-oxo-2H-pyran-2-yl)ethyl]decahydro-3a,9a-dimethyl-6-(1-methylethenyl)-
3-[(1R,3aS,3bS,6S,6aR,7aS,9aR)-6-Isopropenyl-3a,9a-dimethyl-1-{(1S)-1-[(2R)-5-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl}decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid
1H-cyclopenta[a]cyclopropa[e]naphthalene-6a(7H)-propanoic acid, 1-[1-[(2R)-3,6-dihydro-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]decahydro-3a,9a-dimethyl-6-(1-methylethenyl)-, (1R,3aS,3bS,6S,6aR,7aS,9aR)-

Biological Activity

[Description]:

Schisanlactone E is a triterpenoids that can be isolated from Kadsura heteroclita. Schisanlactone E exhibits moderate cytotoxic activity against Bel-7402, BGC-823, MCF-7 and HL-60 cell line with IC50s of 68.33, 100, >100, 73.37 μM,respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Wang W, et al. New triterpenoids from Kadsura heteroclita and their cytotoxic activity. Planta Med. 2006 Apr;72(5):450-7.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
605.3±38.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₄₄O₄

[ Molecular Weight ]:
468.67

[ Flash Point ]:
192.6±20.3 °C

[ Exact Mass ]:
468.323975

[ PSA ]:
63.60000

[ LogP ]:
7.79

[ Vapour Pressure ]:
0.0±3.7 mmHg at 25°C

[ Index of Refraction ]:
1.555

Related Compounds

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