6,7-Dimethoxy-3,4-dihydronaphthalen-1(2H)-one

Names

[ CAS No. ]:
13575-75-2

[ Name ]:
6,7-Dimethoxy-3,4-dihydronaphthalen-1(2H)-one

[Synonym ]:
6,7-dimethoxy-3,4-dihydro-2H-naphthalen-1-one
MFCD00134100
6,7-Dimethoxy-3,4-dihydronaphthalen-1(2H)-one

Chemical & Physical Properties

[ Density]:
1.14g/cm3

[ Boiling Point ]:
358.3ºC at 760mmHg

[ Melting Point ]:
98-100 °C(lit.)

[ Molecular Formula ]:
C₁₂H₁₄O₃

[ Molecular Weight ]:
206.23800

[ Flash Point ]:
161.8ºC

[ Exact Mass ]:
206.09400

[ PSA ]:
35.53000

[ LogP ]:
2.22280

[ Vapour Pressure ]:
0.0402mmHg at 25°C

[ Index of Refraction ]:
1.548

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and dopaminergic activity of 2-substituted octahydrobenzo[f]quinolines.

J. Med. Chem. 32 , 961, (1989)

A series of 2-substituted octahydrobenzo[f]quinolines has been synthesized and assayed for dopamine agonist activity. Only the compounds corresponding to the beta-rotameric conformation of dopamine sh...

Substituted benz[a]acridines and benz[c]acridines as mammalian topoisomerase poisons.

Bioorg. Med. Chem. 8(5) , 1171-82, (2000)

Coralyne and several other synthetic benzo[a,g]quinolizium derivatives related to protoberberine alkaloids have exhibited activity as topoisomerase poisons. These compounds are characterized by the pr...

J. Org. Chem. 57 , 5907, (1992)