Vialox

Names

[ Name ]:
Vialox

[Synonym ]:
Pentapeptide-3
L-Alaninamide, glycyl-L-prolyl-N-(diaminomethylene)-L-ornithyl-L-prolyl-
Glycyl-L-prolyl-N-(diaminomethylene)-L-ornithyl-L-prolyl-L-alaninamide
Vialox

Biological Activity

[Description]:

Pentapeptide-3 is a pentapeptide fragment of neurotoxin waglerin-1 from the venom of Temple Viper. Pentapeptide-3 is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), it can blocks nerves at the post-synaptic membrane. Pentapeptide-3 has anti-aging effects and it can be used together with other cosmetic peptides[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Schagen, S.K. Topical peptide treatments with effective anti-aging results. Cosmetics 4(2), 2017.

[2]. Zhmak MN, et al. Peptide inhibitors of nicotinic acetylcholine receptor. WO2014/112902Al, 2017.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₂₁H₃₇N₉O₅

[ Molecular Weight ]:
495.576

[ Exact Mass ]:
495.291779

[ LogP ]:
-2.82

[ Index of Refraction ]:
1.691

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds

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