N-(Trimethylsilyl)acetamide
Names
[ CAS No. ]:
13435-12-6
[ Name ]:
N-(Trimethylsilyl)acetamide
[Synonym ]:
EINECS 236-565-7
N-Trimethylsilylacetamide,TMS acetamide
N-(Trimethylsilyl)acetamide
N-Trimethylsilylacetamide
MFCD00008671
N-TMS-acetamide
Acetamide, N-(trimethylsilyl)-
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
190.2±0.0 °C at 760 mmHg
[ Melting Point ]:
46-49 °C(lit.)
[ Molecular Formula ]:
C5H13NOSi
[ Molecular Weight ]:
131.248
[ Flash Point ]:
57.2±0.0 °C
[ Exact Mass ]:
131.076645
[ PSA ]:
29.10000
[ LogP ]:
0.60
[ Vapour Pressure ]:
0.5±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.406
[ Storage condition ]:
Flammables area
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AD0250000
- CHEMICAL NAME :
- Acetamide, N-(trimethylsilyl)-
- CAS REGISTRY NUMBER :
- 13435-12-6
- BEILSTEIN REFERENCE NO. :
- 0741928
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C5-H13-N-O-Si
- MOLECULAR WEIGHT :
- 131.28
- WISWESSER LINE NOTATION :
- 1VM-SI-1&1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Immunological Including Allergic - decreased immune response
- REFERENCE :
- StoGD# Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975 Volume(issue)/page/year: 27MAY1975
Safety Information
[ Hazard Codes ]:
F:Flammable;Xi:Irritant;
[ Risk Phrases ]:
R11;R36/37/38
[ Safety Phrases ]:
S37/39-S26
[ RIDADR ]:
1325
[ WGK Germany ]:
3
[ RTECS ]:
AD0250000
[ Packaging Group ]:
III
[ Hazard Class ]:
4.1
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
J. Chromatogr. A. 26 , 22, (1967)
D.R. Knapp
Handbook of Analytical Derivatization Reactions , (1979), 572
Quantitative analysis of ascorbic acid in tissues by gas-liquid chromatography.
Anal. Biochem. 43 , 401, (1971)