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1-Galloyl-beta-glucose

Names

[ CAS No. ]:
13405-60-2

[ Name ]:
1-Galloyl-beta-glucose

[Synonym ]:
[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] 3,4,5-trihydroxybenzoate
1-O-Galloyl-β-D-glucose
1-Galloyl-beta-glucose
β-Glucogalin

Biological Activity

[Description]:

β-Glucogallin is a potent and selective aldose reductase (AKR1B1) inhibitor. β-Glucogallin can be isolated from the medicinal plant Emblica officinalis[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase
Research Areas >> Metabolic Disease

[References]

[1]. Li L, et al. Design of an amide N-glycoside derivative of β-glucogallin: a stable, potent, and specific inhibitor of aldose reductase. J Med Chem. 2014 Jan 9;57(1):71-7.  

Chemical & Physical Properties

[ Density]:
1.85

[ Melting Point ]:
214℃

[ Molecular Formula ]:
C13H16O10

[ Molecular Weight ]:
332.26000

[ Exact Mass ]:
332.07400

[ PSA ]:
177.14000

[ Vapour Pressure ]:
9.04E-23mmHg at 25°C

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream


Related Compounds