IRE1α kinase-IN-9

Names

[ CAS No. ]:
1338933-30-4

[ Name ]:
IRE1α kinase-IN-9

Biological Activity

[Description]:

IRE1α kinase-IN-9 (compound 2) is a potent IRE-1α inhibitor，exhibits an average IC50 value of <0.1 μM. IRE1α kinase-IN-9 can be used for research in diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> IRE1

[Target]

IC50: <0.1 μM (IRE1α)[1]


[References]

[1]. Zeng Q, et al. Benzoheterocyclecarboxaldehyde derivatives as IRE-1α inhibitors and their preparation and use for the treatment of diseases. World Intellectual Property Organization, WO2011127070 A2. 2011-10-13.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H24N2O6

[ Molecular Weight ]:
436.46

Related Compounds