Tr-PEG3-OH

Names

[ Name ]:
Tr-PEG3-OH

[Synonym ]:
Ethanol,2-[2-[2-(triphenylmethoxy)ethoxy]ethoxy]
Tr-PEG4
1-hydroxy-8-trityloxy-3,6-dioxaoctane
10,10,10-triphenyl-3,6,9-trioxadecan-1-ol
2-(2-(2-(trityloxy)ethoxy)ethoxy)ethanol
triethylene glycol monotrityl ether
8-(triphenylmethyloxy)-3,6-dioxaoctan-1-ol
10,10,10-Triphenyl-3,6,9-trioxadecanol

Biological Activity

[Description]:

Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

Research Areas >> Inflammation/Immunology

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Chou CH, et al. Glycan-Directed Grafting-from Polymerization of Immunoglobulin G: Site-Selectively Modified IgG-Polymer Conjugates with Preserved Biological Activity. Biomacromolecules. 2018 Jul 9;19(7):3086-3095.

Chemical & Physical Properties

[ Density]:
1.126±0.06 g/cm3(Predicted)

[ Boiling Point ]:
521.8±45.0 °C(Predicted)

[ Molecular Formula ]:
C₂₅H₂₈O₄

[ Molecular Weight ]:
392.48700

[ Exact Mass ]:
392.19900

[ PSA ]:
47.92000

[ LogP ]:
4.02060

Precursor & DownStream

Precursor

DownStream

Related Compounds

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