N-SUCCINYL-ILE-ILE-TRP 7-AMIDO-4-METHYLCOUMARIN

Names

[ Name ]:
N-SUCCINYL-ILE-ILE-TRP 7-AMIDO-4-METHYLCOUMARIN

[Synonym ]:
4-[[(2S,3S)-1-[[(2S,3S)-1-[[(2S)-3-(1H-indol-3-yl)-2-[(4-methyl-2-oxochromen-7-yl)amino]propanoyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid

Biological Activity

[Description]:

N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Xiong, et al. Fluorogenic and chromogenic detection of carboxypeptidase Y with a nonpeptide-based small-molecule probe. Sensors and Actuators, B. Chemical, 2018, 269(15):127-134.

Chemical & Physical Properties

[ Density]:
1.282g/cm3

[ Boiling Point ]:
1033.1ºC at 760mmHg

[ Molecular Formula ]:
C₃₇H₄₅N₅O₈

[ Molecular Weight ]:
687.78200

[ Flash Point ]:
578.6ºC

[ Exact Mass ]:
687.32700

[ PSA ]:
199.70000

[ LogP ]:
5.42100

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.612

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Endothelin converting enzyme of porcine lung.

Biochem. Soc. Trans. 21(1) , 27S, (1993)

Endothelin-converting enzyme: the binding of metal ions.

Int. J. Pept. Protein Res. 42(1) , 64-7, (1993)

The metal ion of endothelin-converting enzyme (ECE) was investigated by inhibiting the enzyme with ethylenediaminetetraacetic acid (EDTA) and restoring activity by adding divalent metal salts in quant...

Structure elucidation of a novel funicone-like compound produced by Penicillium pinophilum.

Nat. Prod. Lett. 16(3) , 207-11, (2002)

A novel metabolite related to the previously identified compound 3-O-methylfunicone (1) was isolated from the fungus Penicillium pinophilum and its structure elucidated by spectral analysis as 3-O-met...

Related Compounds

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