2-chloroinosine

Names

[ Name ]:
2-chloroinosine

[Synonym ]:
2-Chloroinosine
2-Chlor-inosin

Biological Activity

[Description]:

2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
2.194 g/cm3

[ Melting Point ]:
141-143ºC (dec.)

[ Molecular Formula ]:
C₁₀H₁₁ClN₄O₅

[ Molecular Weight ]:
302.67

[ Exact Mass ]:
302.04200

[ PSA ]:
133.49000

[ Storage condition ]:
-20°C Freezer

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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