Naphthoresorcinol

Names

[ CAS No. ]:
132-86-5

[ Name ]:
Naphthoresorcinol

[Synonym ]:
EINECS 205-079-7
Naphthalene-1,3-diol
1,3-Naphthalenediol
MFCD00003965
Naphthoresorcinol
1,3-dihydroxynaphthalene
Benzoresorcinol
1,3-Naphthalenediol,Naphthoresorcinol

Biological Activity

[Description]:

Naphthoresorcinol (1,3-Dihydroxynaphthalene) is a fluorescent dye (λex=330 nm, λem=380 nm) that can react with the NPPD (a tracer) and concentrated HCl and develop a red color. Naphthoresorcinol could be used as a background electrolyte (BGE) to determine the carbohydrates[1][2][3].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Vyas S, et, al. Fluorescence and light scattering studies on the interaction of 1,3-dihydroxynaphthalene with ionic and non-ionic surfactants. Polymer Photochemistry. 1984; 4(4):245-253.

[2]. Suzuki S, et, al. Development of a field kit for use by non-scientists for chemical tracking using 5-(4-nitrophenyl)-2,4-pentadien-1-al. Forensic Sci Int. 2013 May 10;228(1-3):e25-7.

[3]. Lee YH, et, al. Determination of carbohydrates by high-performance capillary electrophoresis with indirect absorbance detection. J Chromatogr B Biomed Appl. 1996 May 31;681(1):87-97.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
361.5±9.0 °C at 760 mmHg

[ Melting Point ]:
123-125 °C(lit.)

[ Molecular Formula ]:
C₁₀H₈O₂

[ Molecular Weight ]:
160.169

[ Flash Point ]:
185.5±13.3 °C

[ Exact Mass ]:
160.052429

[ PSA ]:
40.46000

[ LogP ]:
1.99

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.726

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ4725000

CHEMICAL NAME :: 1,3-Naphthalenediol

CAS REGISTRY NUMBER :: 132-86-5

BEILSTEIN REFERENCE NO. :: 2044002

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C10-H8-O2

MOLECULAR WEIGHT :: 160.18

WISWESSER LINE NOTATION :: L66J BQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 625 nmol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 371,293,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6606 No. of Facilities: 73 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 2798 (estimated) No. of Female Employees: 1388 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QJ4725000

[ HS Code ]:
2907299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2907299090

[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

Articles

Selective antiproliferative activity of hydroxynaphthyl-beta-D-xylosides.

J. Med. Chem. 49 , 1932-8, (2006)

The antiproliferative activity of the 14 isomeric monoxylosylated dihydroxynaphthalenes has been tested in vitro toward normal HFL-1 and 3T3 A31 cells as well as transformed T24 and 3T3 SV40 cells. Th...

Mutagenicity of products formed by ozonation of naphthoresorcinol in aqueous solutions.

Mutat. Res. 189(3) , 217-22, (1987)

The mutagenicity of products formed by ozonation of naphthoresorcinol in aqueous solution was assayed with Salmonella typhimurium strains TA97, TA98, TA100, TA102 and TA104 in the presence and absence...

Effector-repressor interactions, binding of a single effector molecule to the operator-bound TtgR homodimer mediates derepression.

J. Biol. Chem. 281(11) , 7102-9, (2006)

The RND family transporter TtgABC and its cognate repressor TtgR from Pseudomonas putida DOT-T1E were both shown to possess multidrug recognition properties. Structurally unrelated molecules such as c...