AUT1

Names

[ Name ]:
AUT1

Biological Activity

[Description]:

AUT1 is a Kv3 potassium channel modulator, with pEC50s of 5.33 and 5.31 for human recombinant Kv3.1b and Kv3.2a, respectively, exhibits 10-fold lower potency at human recombinant Kv3.3 channel (pEC50, 4.5)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[Target]

pEC50: 5.33 (Human recombinant Kv3.1b), 5.31 (Human recombinant Kv3.2a), 4.5 (Human recombinant Kv3.3)[1]

[References]

[1]. Rosato-Siri MD, et al. A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons. J Pharmacol Exp Ther. 2015 Sep;354(3):251-60.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₉N₃O₄

[ Molecular Weight ]:
341.36

[ Storage condition ]:
2-8℃

Related Compounds

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