1311136-84-1

1311136-84-1 structure

Name: AUT1
Chemical Name: AUT1
CAS Number: 1311136-84-1
Molecular Formula: C₁₈H₁₉N₃O₄
Molecular Weight: 341.36
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2019-06-05 17:54:29
Modify Date: 2024-03-04 15:28:40
AUT1 is a Kv3 potassium channel modulator, with pEC50s of 5.33 and 5.31 for human recombinant Kv3.1b and Kv3.2a, respectively, exhibits 10-fold lower potency at human recombinant Kv3.3 channel (pEC50, 4.5)[1].

Name	AUT1

Description	AUT1 is a Kv3 potassium channel modulator, with pEC50s of 5.33 and 5.31 for human recombinant Kv3.1b and Kv3.2a, respectively, exhibits 10-fold lower potency at human recombinant Kv3.3 channel (pEC50, 4.5)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	pEC50: 5.33 (Human recombinant Kv3.1b), 5.31 (Human recombinant Kv3.2a), 4.5 (Human recombinant Kv3.3)[1]
References	[1]. Rosato-Siri MD, et al. A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons. J Pharmacol Exp Ther. 2015 Sep;354(3):251-60.