Modotuximab
Names
[ CAS No. ]:
1310460-86-6
[ Name ]:
Modotuximab
Biological Activity
[Description]:
Modotuximab (Anti-Human EGFR Recombinant Antibody) is an IgG1κ-type chimeric antibody targeting human EGFR protein. Modotuximab contains a portion of Futuximab that binds to two independent, non-overlapping epitopes on EGFR. Modotuximab promotes cross-linking of EGFR on the cell surface and promotes EGFR cellular internalization and degradation. Modotuximab has antitumor activity in vivo[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
No Any Chemical & Physical Properties