Ethyl trifluoropyruvate

Names

[ Name ]:
Ethyl trifluoropyruvate

[Synonym ]:
Ethyl 3,3,3-trifluoro-2-oxopropanoate
Ethyl trifluoropyruvate
Propanoic acid, 3,3,3-trifluoro-2-oxo-, ethyl ester
Trifluoropyruvic acid ethyl ester
Ethyl 2-oxo-3,3,3-trifluoropropanoate
Ethyl 3,3,3-trifluoropyruvate
MFCD00114935
FXFFVVO2
Ethyltrifluoropyruvate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
88.1±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₅F₃O₃

[ Molecular Weight ]:
170.087

[ Flash Point ]:
8.1±22.2 °C

[ Exact Mass ]:
170.019073

[ PSA ]:
43.37000

[ LogP ]:
1.57

[ Vapour Pressure ]:
62.0±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.349

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R10;R36/37/38

[ Safety Phrases ]:
S26-S37/39-S16

[ RIDADR ]:
UN 3272 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Organocatalytic enantioselective Friedel–Crafts alkylation of simple phenols with trifluoropyruvate. Zhao JL, et al.

Tetrahedron Lett. 49(9) , 1476-1479, (2008)

Novel Enantiocomplementary C₂-Symmetric Chiral Bis (imidazoline) Ligands: Highly Enantioselective Friedel–Crafts Alkylation of Indoles with Ethyl 3, 3, 3-Trifluoropyruvate. Nakamura S, et al.

Adv. Synth. Catal. 350(10) , 1443-1448, (2008)

Synthesis of N-Heteroaryl (trifluoromethyl) hydroxyalkanoic Acid Esters by Highly Efficient Solid Acid-Catalyzed Hydroxyalkylation of Indoles and Pyrroles with Activated Trifluoromethyl Ketones. Abid M and Török B.

Adv. Synth. Catal. 347(14) , 1797-1803, (2005)